Articles
Building Resilience with MCAS: Self Care, Sleep and Emotional Wellbeing
PowerPoint slides from Rebecca Fredericks webinar 'Building Resilience with MCAS: Self Care, Sleep and Emotional Wellbeing'.
Building Resilience with MCAS: Self-Care, Sleep, and Emotional Wellbeing Workbook
This workbook is to go alongside the session on Building Resilience with MCAS: Self-Care, Sleep, and Emotional Wellbeing hosted by Rebecca Fredericks.
Mast Cells and The Mind
A PDF to support our session on mast cells and the mind by Deborah Bircham
Prevalence of mast cell activation disorders and hereditary alpha tryptasemia among patients with postural orthostatic tacycardia syndrome and Ehlers-Danlos syndrome: A systematic review
Matthew Farley, Ricardo J. Estrada-Medisabel, Emily A. Gansert, Dayne Voelker, Lisa A. Marks, Alexei Gonzalez-Estrada (2025). This article systematically reviews the prevalence of mast cell activation disorders (MCADs) and hereditary alpha tryptasemia (HAT) in patients with postural orthostatic tachycardia syndrome (POTS) and Ehlers-Danlos syndrome (EDS). It finds that no studies that met strict diagnostic criteria confirm a clear association. Despite anecdotal reports and individual studies suggesting potential overlap between these conditions, most existing research lacked validated diagnostic standards and consistency. The article concludes that more rigorous, well-designed studies are needed to determine whether a true clinical relationship exists among POTS, EDS, MCADs, and HAT.
Prevalence and treatment response of neuropsychiatric disorders in mast cell activation syndrome
Leonard B. Weinstock , Lawrence B. Afrin, Angela M. Reierson, Jill Brook, Svetlana Blitshteyn, Gillian Ehrlich, Jill R. Schofield, Laurence Kinsella, David Kaufman, Tania Dempsey, Gerhard J. Molderings (2025). This article investigates the prevalence of a variety of neuropsychiatric manifestations in MCAS patients in comparison to healthy controls. It finds that MCAS patients have high rates of self-reported neuropsychiatric disorders and symptoms compared to healthy age-matched controls. The study suggests that MCAS subjects may see improvement in comorbid neuropsychiatric disorders using MCAS-targeted therapies, and that genetic predisposition, life experience and mast cell mediators determine which neuropsychiatric conditions have potential to develop.
Seated Pilates Guide
This Seated Pilates guide has been designed especially for those living with Mast Cell Activation Syndrome (MCAS). Leanne is a Pain-Free Movement Specialist and Pilates Teacher with lived experience of multiple chronic illnesses. To use this guide, you might like to pick out an exercise, try it, see how you feel and then if you have no adverse effects try another.
Speaking to Your GP: Language and Tips for Effective Communication
This guide has been created to help you communicate more confidently and effectively with your GP. It offers practical language suggestions that can help you explain your symptoms, request support, and build a more collaborative relationship, whether you have a confirmed diagnosis or are still seeking answers.
Gratitude
PowerPoint Slides from Deborah Bircham from Live Well with Chronic Illness webinar 'Gratitude' exploring what is Gratitude, and how can it help us.
Navigating the Storm
PowerPoint Slides from Dr. Ashlyn Firkins webinar 'Navigating the Storm'. You can find the recording of this session on our YouTube channel.
Understanding Mast Cells, Autoimmune Disorders and Comorbidity
PowerPoint slides from Roselle O'Brien's talk 'Understanding Mast Cells, Autoimmune Disorders and Comorbidities'. You can find the recording of this session on our YouTube channel.
Navigating Diagnosis: Support and Guidance for the MCAS Community
This guide is designed to support individuals in the MCAS community who are navigating the challenges of seeking a diagnosis.
MCAS and Related Conditions - Special Consideration for Anaesthesia Surgery with Dr. Anton Krige
PowerPoint slides from our Dr Anton Krige's webinar 'MCAS and Related Conditions - Special Consideration for Anaesthesia Surgery with Dr. Anton Krige'. You can find the recording of this session on our YouTube channel.
Gratitude Handout
Use this journal however feels right for you. There’s no pressure to write every day or find something profound. Some days, it might be a kind word from a friend, a moment of peace, or simply managing to eat a safe meal. These moments matter. You matter.
Potato lectin activates basophils and mast cells of atopic subjects by its interaction with core chitobiose of cell-bound non-specific immunoglobulin E
S. N. Pramod, Y. P. Venkatesh and P. A. Mahesh (2007). This study addresses the role of potato lectin (STA) in activating mast cells and basophils through non-specific binding to IgE and FcεR receptors. It studies the effect of STA on atopic and non-atopic subjects, and finds that it may cause non-allergic hypersensitivity in some atopic individuals, despite not being a ‘true allergen’. Therefore, it suggests that lectins in foods like potatoes and tomatoes may contribute to symptoms of allergic reactions (e.g. asthma) in STA-sensitive individuals.
Retrain Your Brain, Retrain Your Mast Cells
PowerPoint slides from Roselle O'Brien's webinar 'Retrain Your Brain, Retrain Your Mast Cells'. You can find the recording of this session on our YouTube channel.
Foods and Inflammation
PowerPoint slides from Deborah Bircham's from Live Well with Chronic Illness webinar 'Foods and Infammation'. You can find the recording of this session on our YouTube channel.
Dysautonomia
PowerPoint slides from Roselle O Brien's webinar 'Dysautonomia'. You can find the recording of this session on our YouTube channel.
Your Safe Haven at Home
PowerPoint slides from Roselle O Brien's webinar on 'Your Safe Haven at Home'. You can find the recording of this session on our YouTube channel.
MCAS and Environmental Pollution the Toxic Truth
PowerPoint slides from Deborah Bircham's from Live Well with Chronic Illness' webinar 'MCAS and Environmental Pollution the Toxic Truth'. You can find the recording of this session on our YouTube channel.
What is detoxing and how might it help with MCAS?
PowerPoint slides from Deborah Bircham's from Live Well with Chronic Illness' webinar on 'What is detoxing and how might it help with MCAS?'. You can find the recording of this session on our YouTube channel.
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