Articles
Three children's stories
A comparative review of three paediatric case examples - could mast cell activation and mast cell mediators be a cause of the multiple symptoms experienced by children like Lily, Jensen and Caspyn?
Mast Cell Action Brochure; September 2020
Our brochure about MCAS, including what is MCAS? Triggers and symptoms, diagnosis and management.
Parent support leaflet
A leaflet designed to help support parents and carers of children living with systemic mast cell activation and MCAS. It provides suggestions for how to care for your personal wellbeing whilst caring for someone with MCAS, and shares ideas and suggestions for how to communicate and support each other as a family.
Suzy's story
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Jackie's story
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Feel good jar
An exercise to help you find the activities that make you feel good and may help to improve your mood. Suitable for children and adults.
Perceived stress scale - Adults
This worksheet helps you to estimate your personal stress levels and gives you an idea of your current wellbeing.
Mood check-in sheet - children
This is a quick and easy resource designed to help you, and those that care about you, to check-in with how you are doing.
Mood check in sheet - Adult
This is a quick and easy resource designed to help you, and those that care about you, to check-in with how you are doing.
The 2011 consensus diagnostic criteria for MCAS - a one page to print out for a doc
Definitions, Criteria and Global Classification of Mast Cell Disorders with Special Reference to Mast Cell Activation Syndromes: A Consensus Proposal Peter Valent, et al. 2011.
Bibliography of MCAS papers
An easy to use summary of key MCAS papers, with hypertext links to the publications, 2018
Elevated Tryptase Associated With Atopy and Connective Tissue Abnormalities"
In this interview, JACI Associate Editor Dr. Deborah Meyers talks to Dr. Joshua Milner about his article "Mendelian Inheritance Of Elevated Tryptase Associated With Atopy and Connective Tissue Abnormalities"
Serum mast cell tryptase measurements: Sensitivity and specificity for a diagnosis of anaphylaxis in emergency department patients with shock or hypoxaemia
Francis A, Fatovich DM, Aren. Serum mast cell tryptase measurements: Sensitivity and specificity for a diagnosis of anaphylaxis in emergency department patients with shock or hypoxaemia. Emerg Med Australas. 2017 Nov 2.
A Practical Guide for Treatment of Pain in Patients with Systemic Mast Cell Activation Disease
Wirz S, Molderings GJ. A Practical Guide for Treatment of Pain in Patients with Systemic Mast Cell Activation Disease. Pain Physician. 2017 Sep;20(6):E849-E861.
"New" tests for MCAS available in the UK
Sheffield Protein Reference Unit tests for mast cell activation markers
Mast cell activation syndromes
Akin C. Mast cell activation syndromes. J Allergy Clin Immunol. 2017 Aug;140(2):349-355. PMID: 28780942 DOI: 10.1016/j.jaci.2017.06.007
Characterization of Mast Cell Activation Syndrome
Mast cell activation syndrome (MCAS), a recently recognized nonneoplastic mast cell disease driving chronic multisystem inflammation and allergy, appears prevalent and thus important. We report the first systematic characterization of a large MCAS population.
Mast cell disorders in Ehlers-Danlos syndrome
This report reviews basic biology of mast cells and mast cell activation as well as recent research efforts, which implicate a role of MC dysregulation beyond atopic disorders and in a cluster of Ehlers-Danlos Syndromes, non-IGE mediated hypersensitivity disorders, and dysautonomia.
Info on Recent International Disease Code (ICD10) codification of MCAS
The coding of MCAS into the ICD-10 (American version) is an important step in gaining better recognition of MCAS.
Comparative analysis of mutation of tyrosine kinase kit in mast cells from patients with systemic mast cell activation syndrome and healthy subjects.
Molderings GJ, Meis K, Kolck UW et al. Comparative analysis of mutation of tyrosine kinase kit in mast cells from patients with systemic mast cell activation syndrome and healthy subjects. Immunogenetics. 2010 Dec;62(11-12):721-7.
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